Chronic mucocutaneous candidiasis is a derivative of immunodeficiency disease in which T lymphocytes damaged. Because T lymphocytes is damaged, the body is less able to fight fungal infections, including yeast infections. The ability to fight other infections are not reduced. Infection with Candida fungi (candidiasis) develop and survive, usually begin during infancy but occasionally during early adulthood.
Fungi may cause mouth infections (thrush) as well as infections of the scalp; skin; nails; and membranes throughout the mouth, eyes, digestive tract, and reproductive tract. Severity varies: the disease can affect one nail or cause spotting a rash that covers the face and scalp. Hair may fall out. Hepatitis and chronic lung disease sometimes develops. Many people also experience endocrine disorders, such as underactive parathyroid glands (hypoparathyroidism).
Usually, the infection can be treated with antifungal drug nystatin or clotrimazole is applied to the skin. Infection is severe, rare, require more powerful antifungal drugs, such as itraconazole given by mouth. Typically, the disease is chronic but does not affect survival.
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